Description
Long-acting amylin analog for weight management
Cagrilintide is a lab-developed peptide that aids in appetite suppression and promotes meaningful weight loss. Acting as an analog of the naturally occurring hormone amylin, Cagrilintide slows gastric emptying and enhances feelings of fullness. Helps regulate appetite and support a sustained calorie deficit, contributing to fat loss and metabolic function. Also shown promise in improving cardiovascular markers by assisting with weight reduction.
- Lau DCW, et al. Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial. Lancet. 2021;398(10317):2160-2172. PMID: 34798060 | DOI: 10.1016/S0140-6736(21)01751-7
- Kruse T, et al. Development of Cagrilintide, a Long-Acting Amylin Analogue. J Med Chem. 2021;64(15):11183-11194. PMID: 34288673 | DOI: 10.1021/acs.jmedchem.1c00565
- D’Ascanio AM, Mullally JA, Frishman WH. Cagrilintide: A Long-Acting Amylin Analog for the Treatment of Obesity. Cardiol Rev. 2024;32(1):83-90. PMID: 36883831 | DOI: 10.1097/CRD.0000000000000513
