Description
ERR agonist / exercise mimetic
SLU-PP-332 is a potent small-molecule ERR agonist known for its ability to enhance mitochondrial function. Through activation of ERRα, ERRβ, and ERRγ nuclear receptors, has been shown to promote fat oxidation and boost energy expenditure. Supports improved metabolic efficiency and is especially relevant for studies related to obesity and metabolic disorders.
References
- Billon C, et al. A Synthetic ERR Agonist Alleviates Metabolic Syndrome. J Pharmacol Exp Ther. 2024;388(2):232-240. PMID: 37739806 | DOI: 10.1124/jpet.123.001733
- Billon C, et al. Synthetic ERRalpha/beta/gamma Agonist Induces an ERRalpha-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol. 2023;18(4):756-771. PMID: 36988910 | DOI: 10.1021/acschembio.2c00720
- Billon C, et al. An orally active estrogen receptor-related receptor agonist, SLU-PP-915, enhances aerobic exercise capacity. J Pharmacol Exp Ther. 2026;393(1):103787. PMID: 41421047 | DOI: 10.1016/j.jpet.2025.103787
Note: Listed as ‘SLU-PP-322’ on the price sheet; the compound in the literature is SLU-PP-332.
